ACANTHUS ILICIFOLIUS PDF

Acanthus ilicifolius Devbagh beach resort. A mangrove species. Located in the deltaic region formed by the rich alluvial deposits of Brahmani, Baitarani and the Mahanadi, Dhamra River, orissa in gereral and Bhitarkanika in perticular is the second largest mangrove ecosystem in the world after Papua New Guinea in terms of species diversity. There are 62 species of mangrove found in Bhitarkanika which includes 32 true mangroves and the rest are assocites.

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The extract showed graded analgesic activity ranging from The ED50 was 2. Graded protective effect ranging from The ED50 of the extract administered was The extract decreased protein exudation and leukocyte migration in the peritoneal fluid, thereby indicating its effectiveness towards inhibiting peritoneal inflammation. It also produced significant inhibition of cyclooxygenase 1 and 2 and lipooxygenase activity.

Preincubation of the extract inhibited the production of proinflammatory cytokines in lipopolysaccharide-stimulated peripheral blood mononuclear cells. No mortality was observed in mice when BOA was administered i. Its effects were tested on the functions of osteoblastic MC3T3-E1 cells. It increased the growth and differentiation of osteoblasts significantly, indicating that A. The air-dried whole plant was sequentially extracted by n-hexane, chloroform, and methanol.

The extracts were fractionated with ethyl acetate, acetone, and water. All the extracts and fractions were tested for anti-cancer activity by comet assay. Ethyl acetate extract of the whole plant showed significant anti-cancer activity.

In both models, common parameter determined was the ulcer index. The extract showed significant reduction in the gastric volume, free acidity, and ulcer index as compared to control. This suggests leaf methanolic extracts were found to possess anti-ulcerogenic as well as ulcer healing properties, which might be due to anti-secretary activity. Ampicillin and clotrimazole were used as standard anti-bacterial and anti-fungal agents, respectively.

The result of the study revealed that the n-hexane and chloroform extract of the leaves exhibited strong inhibitory action against Bacillus subtilis, Staphylococcus aureus, Candida albicans, Aspergillus fumigatus, and Aspergillus niger and moderate inhibitory action against Pseudomonas aeruginosa and Proteus vulgaris. These created an interest to test the possible anti-microbial activity of different part of this plant, which has not been reported.

The cub-plate agar diffusion method was employed to assess the activity. The result of the study revealed that the alcoholic and chloroform extract of the leaves exhibited strong inhibitory action against Bacillus subtilis, Staphylococcus aureus, Candida albicans, Aspergillus fumigatus, and Aspergillus niger and moderate inhibitory action against Pseudomonas aeruginosa and Proteus vulgaris.

It is also considered to be a diuretic and is used as a cure for dropsy and bilious swellings. The plant is reported to be used in asthma. The leaves are expectorant, employed as an emollient fomentation in rheumatism and neuralgia. The leaves and tender shoot are used in snake bite. The root is expectorant and used in asthma.

This when boiled in milk is used in leucorrhoea and general debility. Ethnobotanical Studies The plant is used for dyspepsia, paralysis, and asthma.

The leaves are reported to be used in headache, rheumatism, and in skin diseases. Leaves and shoots are used as antidote in snake bite. References 1. Pharmacognotic studies on mangrove Acanthus ilicifolius. Zhongguo Zhong Yao Za Zhi. Mastaller M. Mangroves: The forgotten forest between land and sea. Tropical Press. Acanthicifoline-A new alkaloid from Acanthus ilicifolius.

Pol J Chem. A triterpenoid saponin from the roots of Acanthus ilicifolius. Isolation of 2-Benzoxazolinone from Acanthus ilicifolius. Indian J Pharm Sci. Pentacyclic triterpenoids and sterols from seven species of mangrove. Nair AG, Pouchaname V. J Indian Chem Soc. Flavonoid glycosides from Acanthus ilicifolius L. Nat Med. Bisoxazolinone from the mangrove Acanthus ilicifolius. Indian J Chem. Lignan glucosides from Acanthus ilicifolius.

Two new cyclolignan glycosides from Acanthus ilicifolius. Wahidulla S, Bhattacharjee JJ. Benzoxazinoids from Acanthus ilicifolius. J Indian Inst Sci. Benzoxazinoid glucosides from Acanthus ilicifolius. New aliphatic alcohol and Z Coumaric acid glycosides from Acanthus ilicifolius. Chem Sci Bull. Phenylethanoid and aliphatic alcohol glycosides from Acanthus ilicifolius.

Proof of presence of unusually naturally occurring homologous series of fifteen saturated odd and even fatty acids in Acanthus ilicifolius L. Acanthaceae J Ind Chem Soc. Chemical constituents of Acanthus ilicifolius L. Arch Pharm Res. A New 5,epoxymegastigmane glucoside from Acanthus ilicifolius. Nat Prod Res. Analgesic and antiinfammatory activity of Acanthus ilicifolius Linn.

Indian J Exp Biol. Anti-inflammatory activity of Acanthus ilicifolius. J Ethnopharmacol. Leishmanicidal activity of 2-benzoxazolinone from Acanthus ilicifolius in vitro. Planta Med. Antioxidant and hepatoprotective effect of Acanthus ilicifolius.

Acanthus ilicifolius plant extracts prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model. World J Gastroenterol. Tumour reducing and anticarcinogenic activity of Acanthus ilicifolius in mice.

Potential anticancer activity of Acanthus ilicifolius extracted from the mangroves forest of Karwar, West coast of India. World J Sci Technol. Evaluation of antiulcer activity in the methanol extract of Acanthus ilicifolius leaves in experimental rats. Int J Pharm Ind Res. Khajure V, Rathod JL. Antimicrobial activity of extracts of Acanthus ilicifolius extracted from the mangroves of Karwar coast Karnataka. Recent Res Sci Technol.

Ganesh S, Jannet J. Screening for antimicrobial activity in Acanthus ilicifolius. Arch Appl Sci Res. Hemolytic and antimicrobial effect in the leaves of Acanthus ilicifolius. J Pharmacol Toxicol. Bose S, Bose A. Antimicrobial activity of Acanthus ilicifolius.

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